The HPV Vaccine

New Study Explains Why It’s “Uncertain” If The HPV Vaccine Even Prevents Cervical Cancer

Published
1 day ago on
February 7, 2020

By
Arjun Walia

In Brief

• The Facts:A new study raises concerns and questions about the effectiveness of the HPV and if it really plays any role at all in preventing cervical cancer.
• Reflect On:Are vaccines as effective as they're marketed to be?

A new study published in The Royal Society of Medicine is one of multiple studies over the years that has emerged questioning the efficacy of the HPV vaccine. The researchers conducted an appraisal of published phase 2 and 3 efficacy trials in relation to the prevention of cervical cancer and their analysis showed “the trials themselves generated significant uncertainties undermining claims of efficacy” in the data they used. The researchers emphasized that “it is still uncertain whether human papillomavirus (HPV) vaccination prevents cervical cancer as trials were not designed to detect this outcome, which takes decades to develop.”  The researchers point out that the trials used to test the vaccine may have “overestimated” the efficacy of the vaccine.

A part of the problem, as the study points out, is that it’s unknown as to whether certain infections would clear, or would persist and lead to cervical changes. This is a big point. Every year around the world, approximately 13.1/100,000 women are diagnosed with cervical cancer, so the rate of incidence is quite low. Furthermore, the vaccination is offered to girls aged 9-13, as the study points out, “before sexual debut and naive to HPV infection.”

The study reviewed 35 published papers relating to 12 randomized blinded non-HPV vaccine-controlled Phase 2 and 3 trials of Gardasil and Cervarix conducted from 2001 to 2016 assessing efficacy against cervical cancer and its precursors. Researchers also examined  39 meta-analyses and systematic reviews of HPV vaccine efficacy.

No Evidence HPV Vaccine Prevents Cervical Cancer

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